Vitamin D is one of the oil soluble vitamins in the body.
It itself is not active but is instead converted by successive reactions into calcitriol an active metabolite in the liver and the kidneys.
The life span of latter is few days while that of prior i.e vitamin D is few months.
So one may not fall short of this vitamin levels so easily. But now a days the risk of vitamin d deficiency is rising due to some life style factors. So lets have a glance about the vitamin d functions and its deficiency symptoms.
Vitamin-D function:
The main function of vitamin d-Calcitriol is to regulate Calcium homeostasis, Calcitriol achieves this in three ways:
- It increases intestinal absorption of calcium,
- Reduces the excretion of calcium from urine by kidneys (by stimulating resorption in the distal renal tubules),
- It also mobilizes bone mineral.
In addition to above calcitriol is also has other important function like
a) It is involved in Insulin secretion from pancreas,
b) Synthesis and secretion of parathyroid and thyroid hormones,
c) Inhibition of production of interleukin by activated T lymphocytes and of immunoglobulin by activated B lymphocytes,
d) Differentiation of monocyte precursor cells and modulation of cell proliferation.
Vitamin D deficiency
This vitamin D deficiency may be seen mostly towards the winter season. During this season, the exposure to sun is very low due to intentional decrease in exposure in the intense cold conditions. Or lack of sufficient sun light for people residing in countries of northern latitudes.
Vitamin D is both a vitamin and also a hormone. It synthesized in the skin under the direct influence of sunlight. The ergosterol & cholesterol below the skin converts to vit.D due to interaction of light. Thus, this is the major source of the vitamin. During the times of decrease in exposure to sun, the Vitamin D deficiency symptoms may arise.
Vitamin D deficiency symptoms in adults
1) In adults symptoms like osteomalacia are seen. But due to its ability to mobilize calcium from bones to blood, it is not so effective in treatment of osteomalacia.
2) Even pains and weakness of bones and muscles are possible. It is also one of the contributor to osteoporosis.
3) Sometimes it is shown to present symptoms of Type-II diabetes due to its role in insulin secretion.
4) Vitamin D deficiency may also alter body immunity.
5) Symptoms of depression are also highly linked to this vitamin deficiency
Also in children symptoms of rickets appear due to the deficiency of Calcium in the body.
Vitamin D Foods and their role in Vitamin D deficiency.
Though sunlight is the best source of vitamin D, foods like milk, eggs, cod liver oil, fish etc are some recommended sources.
So during winters when you feel you are less exposed to sunlight, it is good to consume milk, eggs, fish to replenish it.
In times of severe deficiency, doctors advice to take capsules containing cod liver or shark liver oils to replenish the vitamin.
Vitamin D regulation and chances of overdose:
Vitamin d is inactive form as such and by metabolism converts to active form Calcitriol. This formation is triggered when blood calcium or calcitriol levels fall below certain range.
A sensitive feedback mechanism precisely regulates the concentration of Cholecalciferol in the blood. So, though the intake of vitamin D increases by many times yet the blood concentration of cholecalciferol remains normal. Thus high degree of feedback prevents excessive action of vitamin-D
Second, this controlled conversion of vitamin to calcitriol reserves the vitamin D stored in the liver for future use. Once it is converted, it persists in the body for only a few weeks, whereas in the vitamin D form, it can be stored in the liver for many months.
Excess exposure to sunlight does not lead to vitamin D poisoning because there is a limited capacity to form the Vit-D and to take it up from the skin. So sunlight source seems not only natural but also a safe source.
Vitamin-D overdose/ toxicity symptoms
Some infants are sensitive to intakes of vitamin D as low as 50g/d. As excess vitamin d results in elevated calcium concentration. This may lead to contraction of blood vessels, high blood pressure, and calcification of soft tissues.
In adults symptoms of abdominal cramps, nausea,vomiting, calcium stones in kidney can result.
So if you are suspicious of this vitamin health problems, it is good to consult a physician than to decide on your own. This will help you decide if need vitamin-D supplements. And if so in what combinations as it comes with calcium and other herbs.
